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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP16
All Species:
19.7
Human Site:
S422
Identified Species:
43.33
UniProt:
Q9BY84
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BY84
NP_085143.1
665
73102
S422
A
S
L
H
G
F
S
S
S
E
D
A
L
E
Y
Chimpanzee
Pan troglodytes
XP_520751
665
73101
S422
A
S
L
H
G
F
S
S
S
E
D
A
L
E
Y
Rhesus Macaque
Macaca mulatta
XP_001084619
665
73124
S422
A
S
L
H
G
F
S
S
S
E
D
A
L
E
Y
Dog
Lupus familis
XP_543810
663
72657
S419
A
S
L
H
G
F
S
S
S
E
D
A
L
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
O09112
663
68829
A421
G
P
P
D
P
G
E
A
P
K
L
C
K
L
D
Rat
Rattus norvegicus
NP_001100094
661
72804
S418
A
S
L
H
G
F
S
S
E
D
A
M
E
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508628
481
51865
K239
V
E
F
I
E
R
A
K
A
C
N
G
C
V
L
Chicken
Gallus gallus
XP_428887
701
77250
S458
S
V
Q
G
F
T
S
S
E
D
T
L
E
Y
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998405
539
59053
N297
Q
L
L
D
F
E
K
N
L
K
S
V
C
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10038
657
70984
V415
T
S
S
G
T
V
N
V
N
G
K
R
N
M
T
Sea Urchin
Strong. purpuratus
XP_787378
916
99998
S625
I
N
H
P
D
P
A
S
S
N
T
R
V
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.9
93
N.A.
44.2
90.5
N.A.
52.9
77.1
N.A.
54.5
N.A.
N.A.
N.A.
30.5
33.7
Protein Similarity:
100
99.5
99
95.7
N.A.
57.8
94.8
N.A.
60.5
83.4
N.A.
64.5
N.A.
N.A.
N.A.
46.1
47.6
P-Site Identity:
100
100
100
100
N.A.
0
60
N.A.
0
20
N.A.
6.6
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
66.6
N.A.
20
33.3
N.A.
26.6
N.A.
N.A.
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
0
0
0
0
0
19
10
10
0
10
37
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
10
19
0
0
% C
% Asp:
0
0
0
19
10
0
0
0
0
19
37
0
0
10
10
% D
% Glu:
0
10
0
0
10
10
10
0
19
37
0
0
19
37
0
% E
% Phe:
0
0
10
0
19
46
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
19
46
10
0
0
0
10
0
10
0
0
0
% G
% His:
0
0
10
46
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
19
10
0
10
0
0
% K
% Leu:
0
10
55
0
0
0
0
0
10
0
10
10
37
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
0
10
0
0
0
0
10
10
10
10
10
0
10
0
10
% N
% Pro:
0
10
10
10
10
10
0
0
10
0
0
0
0
0
10
% P
% Gln:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
19
0
0
0
% R
% Ser:
10
55
10
0
0
0
55
64
46
0
10
0
0
0
0
% S
% Thr:
10
0
0
0
10
10
0
0
0
0
19
0
0
0
10
% T
% Val:
10
10
0
0
0
10
0
10
0
0
0
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
55
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _